TLR6 ELISA Kit for Human(Homo sapiens) | EIAab.comTLR6 ELISA Kit for Human(Homo sapiens)

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TLR6 (Gene name),

Toll-like receptor 6 (Protein name ), TLR6_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

TLR6;

Protein name:

Toll-like receptor 6;

Alternative:

CD:

CD286;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Binds TLR2 via their respective extracellular domains. Binds MYD88 via their respective TIR domains.

Function:

Participates in the innate immune response to Gram-positive bacteria and fungi. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2.

Subcellular Location:

Cell membrane Single-pass type I membrane protein Cytoplasmic vesicle phagosome membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

796

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

796:

LKALMTQRTY | LQWPKEKSKR | GLFWANIRAA | FNMKLTLVTE | NNDVKS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q9Y2C9

UniGene:

Hs.575090

SMR:

Q9Y2C9

KEGG:

hsa:10333

STRING:

9606.ENSP00000371376

Pfam:

PF01463

MIM:

605403

Uniprot:

Q9Y2C9

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ELISA Kit for Human Toll-like receptor 6

Cat.:

E0683m

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96T

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ELISA Kit for Human Toll-like receptor 6

Cat.:

E0683h

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96T

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ELISA Kit for Human Toll-like receptor 6

Cat.:

E0683b

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Packing:

96T

CLIA Kit for Human Toll-like receptor 6

Cat.:

U0683m

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Packing:

96T

CLIA Kit for Human Toll-like receptor 6

Cat.:

U0683h

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MSDS:

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Packing:

96T

CLIA Kit for Human Toll-like receptor 6

Cat.:

U0683b

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Packing:

96T

Polyclonal Antibody for Human Toll-like receptor 6

Cat.:

P0683Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Toll-like receptor 6

Cat.:

P0683Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Toll-like receptor 6

Protein for Human Toll-like receptor 6

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"TLR6: a novel member of an expanding Toll-like receptor family."
Takeuchi O. , Kawai T. , Sanjo H. , Copeland N.G. , Gilbert D.J. , Jenkins N.A. , Takeda K. , Akira S.
Gene231:59-65(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Placenta.
2.

"Natural selection in the TLR-related genes in the course of primate evolution."
Nakajima T. , Ohtani H. , Satta Y. , Uno Y. , Akari H. , Ishida T. , Kimura A.
Immunogenetics60:727-735(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT PRO-249
3.

"The novel allele of toll-like receptor 6 gene."
Liu Z. , Xiao W. , Wang J. , Li N. , Tai Y.
Submitted (2007-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS THR-120 AND PRO-249; MET-327
4.

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT PRO-249
5.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);VARIANT PRO-249
7.

"Cooperation of Toll-like receptor 2 and 6 for cellular activation by soluble tuberculosis factor and Borrelia burgdorferi outer surface protein A lipoprotein: role of Toll-interacting protein and IL-1 receptor signaling molecules in Toll-like receptor 2 signaling."
Bulut Y. , Faure E. , Thomas L. , Equils O. , Arditi M.
J. Immunol.167:987-994(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
8.

"CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer."
Stewart C.R. , Stuart L.M. , Wilkinson K. , van Gils J.M. , Deng J. , Halle A. , Rayner K.J. , Boyer L. , Zhong R. , Frazier W.A. , Lacy-Hulbert A. , El Khoury J. , Golenbock D.T. , Moore K.J.
Nat. Immunol.11:155-161(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH CD36 AND TLR4;SUBCELLULAR LOCATION
9.

"Functional characterization of naturally occurring genetic variants in the human TLR1-2-6 gene family."
Ben-Ali M. , Corre B. , Manry J. , Barreiro L.B. , Quach H. , Boniotto M. , Pellegrini S. , Quintana-Murci L.
Hum. Mutat.32:643-652(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS THR-120; VAL-128; PRO-194; THR-210; GLY-210; LYS-247; PRO-249; VAL-283; MET-327; ALA-427; ALA-442; ILE-465; THR-474; VAL-474; VAL-592; THR-690 AND HIS-708;CHARACTERIZATION OF VARIANTS VAL-128; PRO-194; VAL-474; THR-690 AND HIS-708

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